Hotel In Greenville - Vacation Rentals in Jefferson Center

Fire Station One Boutique Hotel From US $309
         

9.4 (13 Reviews)
Hotel
  • Air Conditioner
  • Wheelchair Accessible
  • Accessibility
Colony House Motor Lodge From US $132
         

9.8 (83 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Hotel Roanoke & Conference Center, Curio Collection by Hilton From US $212
         

The Promissory Hotel From US $168
         

9.6 (34 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Wheelchair Accessible
The Liberty Trust From US $316
         

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8.8 (664 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Wheelchair Accessible
Hotel Roanoke & Conference Ctr, Curio Collection by Hilton From US $204
         

Hampton Inn & Suites - Roanoke-Downtown, VA From US $192
         

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8.8 (263 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly
The Liberty Trust From US $173
         

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9.2 (1308 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • TV
SpringHill Suites by Marriott Roanoke From US $212
         

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8.8 (140 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Holiday Inn Express & Suites Roanoke – Civic Center by IHG From US $110
         

Holiday Inn Express & Suites - Roanoke – Civic Center From US $145
         

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8.7 (697 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
SpringHill Suites by Marriott Roanoke From US $172
         

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9.0 (1006 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Hampton Inn and Suites Roanoke Airport/Valley View Mall From US $120
         

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8.6 (232 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Hampton Inn & Suites Roanoke-Downtown From US $169
         

9.0 (1002 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly
Home2 Suites by Hilton Roanoke From US $121
         

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8.4 (553 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly
Hilton Garden Inn Roanoke From US $145
         

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9.0 (1001 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • TV
Courtyard by Marriott Roanoke Airport From US $159
         

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8.3 (283 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Courtyard by Marriott Roanoke Airport From US $157
         

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9.0 (864 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Pro Tip: Hotelingreenville makes it easy to compare the best listings on Hotelingreenville homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between Hotelingreenville homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Jefferson Center.

Weather in Jefferson Center

View the weather forecast for Jefferson Center before booking your Jefferson Center Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Jefferson Center Vacation Rental Frequently Asked Questions

What are the top vacation rentals in Jefferson Center?

There are a lot of options in Jefferson Center. If you plan on staying in the Jefferson Center area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Jefferson Center:

How many vacation rentals are available in Jefferson Center?

Currently, the total number of properties listed in 2026 is over 42 in the Jefferson Center area, and still counting. By aggregating listings from multiple websites, offers an immense amount of choice of the best properties in Jefferson Center.