Hotel In Greenville - Vacation Rentals in Central Business District

Dartmouth House Inn From US $179
         

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9.4 (113 Reviews)
Hotel
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Hampton Inn & Suites Rochester Downtown From US $212
         

9.6 (641 Reviews)
Hotel
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  • Pool
Oakfield Hotel & Suites Rochester, an Ascend Collection Hotel From US $175
         

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9.2 (93 Reviews)
Hotel
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  • Parking
  • Designated Smoking Area
Dartmouth House Inn From US $204
         

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9.6 (228 Reviews)
Hotel
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Residence Inn Rochester Henrietta From US $220
         

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9.1 (66 Reviews)
Hotel
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  • Pet Friendly
Residence Inn by Marriott Rochester Henrietta From US $173
         

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9.2 (602 Reviews)
Hotel
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  • Pet Friendly
Hampton Inn & Suites Rochester Downtown From US $289
         

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8.8 (316 Reviews)
Hotel
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  • Parking
  • Pool

Luxury Places to Stay in Central Business District

Over 582+ Luxury Places to Stay in or Near Central Business District
Spacious Rochester Home w/Heated Pool & Hot Tub! From US $1,826
         

Spacious Rochester Home w/Heated Pool & Hot Tub! From US $1,248
         

9.8 (40 Reviews)
House
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  • Pet Friendly
Family Retreat: Sleeps 16+ Near U of R From US $1,095
         

New
House
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Spacious Rochester Home w/Heated Pool & Hot Tub! From US $980
         

Family and Wellness Retreat Sleeps 8 Near RGH From US $851
         

New
House
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Family Retreat: Sleeps 16+ Near U of R From US $707
         

New
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Top-Rated Vacation Rentals with a Pool in Central Business District

Over 51+ Top-Rated Vacation Rentals with a Pool in or Near Central Business District
Amazing ranch located in Henrietta, pool and king size master bed. From US $274
         

Life Just Got Better at 12 Corners. Convenient. Pool. From US $462
         

10.0 (24 Reviews)
House
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  • Pet Friendly
Great Studio | Free Breakfast From US $260
         

10.0 (1 Review)
Apartment
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Convenience Meets Comfort & Cozy From US $111
         

10.0 (1 Review)
Apartment
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  • Parking
  • Pet Friendly
Hampton Inn Rochester Penfield From US $121
         

9.0 (1005 Reviews)
Hotel
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  • Pool
Hilton Garden Inn Rochester/University & Medical Center From US $204
         

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9.0 (1004 Reviews)
Hotel
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  • Pool
Hampton Inn & Suites Rochester/Henrietta From US $149
         

9.0 (1002 Reviews)
Hotel
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  • Parking
  • Pool

Pet-Friendly Vacation Rentals in Central Business District

Over 232+ Pet-Friendly Vacation Rentals in or Near Central Business District
1 Queen Bed | ADA/RI Shower/Non-Smoking/Kitchen From US $87
         

10.0 (41 Reviews)
Apartment
  • Air Conditioner
  • Pet Friendly
  • TV
Studio w/King bed Near Dwtd From US $247
         

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10.0 (3 Reviews)
Apartment
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  • Pet Friendly
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Red Roof Inn Rochester – Airport From US $89
         

5.2 (1001 Reviews)
Hotel
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  • Pet Friendly
1 King Bed | Non-Smoking, Kitchen, Shower From US $91
         

10.0 (37 Reviews)
Apartment
  • Air Conditioner
  • Pet Friendly
  • TV
2 Full Beds | Non-Smoking, Kitchen From US $98
         

10.0 (29 Reviews)
Apartment
  • Air Conditioner
  • Pet Friendly
  • TV
Spacious 4 BDRM w/Onsite Parking & A/C! From US $196
         

10.0 (24 Reviews)
House
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  • Parking
  • Pet Friendly
Minutes from UofR- Large 3BDRM! From US $241
         

10.0 (14 Reviews)
House
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  • Pet Friendly
Cozy Home Near URMC, RIT, Strong From US $293
         

10.0 (9 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly

Large Vacation Homes & Villas in Central Business District

Over 74+ Large Vacation Homes & Villas in or Near Central Business District
The Roc-House Airport Home Office Gaming Center From US $312
         

9.8 (25 Reviews)
House
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  • TV
  • Security/Safety
Live in sophistication and elegance in your VRBO home From US $518
         

5 br|Parking | Mins to RIT, UR & Strong From US $330
         

9.4 (9 Reviews)
House
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  • TV
5 BR Bethesda House 5 Beds From US $603
         

8.8 (23 Reviews)
House
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2 Miles to Dtwn! Idyllic Rochester Apt w/Hot Tub From US $163
         

8.2 (50 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pool

Wheelchair Accessible Vacation Homes in Central Business District

Over 93+ Wheelchair Accessible Vacation Homes in or Near Central Business District
A Symphony of Class and Comfort From US $180
         

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9.8 (30 Reviews)
Villa
  • Air Conditioner
  • Parking
  • Wheelchair Accessible
Staybridge Suites Rochester University by IHG From US $200
         

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9.0 (1002 Reviews)
Hotel
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  • Parking
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Fresh, Sleek, and Contemporary Executive Apartment From US $176
         

10.0 (1 Review)
Apartment
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  • Parking
  • Pet Friendly
1 Queen Bed | Non-Smoking, Kitchen From US $87
         

9.8 (37 Reviews)
Apartment
  • Air Conditioner
  • Pet Friendly
  • TV
East 116 I Corporate 1Bd Suite in Rochester I Gym From US $134
         

Central Business District Vacation Rentals and Airbnb Places to Stay Under $200

Over 303+ Central Business District Vacation Rentals and Airbnb Places to Stay Under $200
New/Quiet/Woodsy n2 min-490/590-City From US $138
         

10.0 (13 Reviews)
Apartment
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Studio w/King Bed near Dwtn From US $147
         

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10.0 (2 Reviews)
Apartment
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Cozy Ranch From US $161
         

10.0 (6 Reviews)
House
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  • Parking
  • TV
Oxford-Park Avenue Luxury Suite From US $175
         

10.0 (4 Reviews)
Apartment
  • Parking
  • TV
  • Balcony/Terrace
4 Mi to Dtwn Rochester: Charming Apt w/Patio! From US $180
         

10.0 (3 Reviews)
Apartment
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Beautiful 1 Bed Near All Attractions From US $197
         

10.0 (1 Review)
Apartment
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  • Parking
  • Pet Friendly

Instantly Bookable Vacation Homes in Central Business District

Over 284+ Instantly Bookable Vacation Homes in or Near Central Business District
Park Avenue 3 bedroom, enjoy everything the neighborhood has to offer! From US $214
         

8.0 (1 Review)
House
  • Security/Safety
  • Bedding/Linens
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*Luxury 3 Bed 2.5 Bath/Prime Park Ave. Location* From US $287
         

Fresh Modern Apartment - Walking Distance to U of R/Strong Hospital From US $212
         

Brighton Retreat Near URMC & Pittsford Plaza From US $501
         

10.0 (3 Reviews)
House
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  • Pet Friendly
Spacious Modern Family Home - Prime Location From US $314
         

10.0 (2 Reviews)
House
  • Air Conditioner
  • Parking
  • TV

About Central Business District Vacation Rentals

With more than 62 Central Business District vacation rentals, we can help you find a place to stay. These rentals, including vacation rentals, Hotelingreenville and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at a rental property in Central Business District.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With Hotelingreenville Central Business District, you have the flexibility of comparing different options of various deals with a single click. Looking for a rental by owner with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner, and other popular Airbnb-style properties in Central Business District. Places to stay near Central Business District are 184.9 ft² on average, with prices averaging US $163 a night.

Hotelingreenville makes it easy and safe to find and compare vacation rentals in Central Business District with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

Top Rental Accommodation Types in Central Business District

Type Count
Hotels 62

Use these Quick Filters to Find a Vacation Rental in Central Business District

Pro Tip: Hotelingreenville makes it easy to compare the best listings on Hotelingreenville homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between Hotelingreenville homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Central Business District.

Weather in Central Business District

View the weather forecast for Central Business District before booking your Central Business District Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Central Business District Vacation Rental Frequently Asked Questions

What are the top vacation rentals in Central Business District?

There are a lot of options in Central Business District. If you plan on staying in the Central Business District area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Central Business District:

How many vacation rentals are available in Central Business District?

Currently, the total number of properties listed in 2026 is over 62 in the Central Business District area, and still counting. By aggregating listings from multiple websites, offers an immense amount of choice of the best properties in Central Business District.